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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cc5ec278071b7a5751d3e1a5af27d4f3e2afe27cb69e7293ec3ef9d3c5e4e4b' 
  AND token = 'a4R9HxSDNtQe5fmpEC05LFf2yJM9Fj5nbHOqWbkznPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}