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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f778dd82ce0e023bdc1dee6d2a5025d3515f738852792fd31d3dd1182bbc92c7' 
  AND token = 't+BTvNTx5v86tbMDphaOr7FjhvNIOGs4zgkpExynW4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}