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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd278a866c5e166f7be825057e6056ab5ef9f4f1134a3b37348f6500f7897aaf' 
  AND token = 'L5HMo3getpe+wyXHI0gGoM63qySSuC9rTn9+7r73eys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}