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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3398e4c087013dfead80b0f514b74544630ef0ad3f2ced4d4da895c1c9a1622' 
  AND token = 'SnIOPazixpxFxAf0pRxkeoMtqexyOQA5lxKI68iNreo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}