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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c0110a49deef1db6297083fcfd2636f3c522e45e15047a0dca5c865d0d72c3c' 
  AND token = 'qB6ZM8gMJyws/v2i21kO3icSQSah9tgRpfgltkRWcL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}