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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e34a6e4f6c73322a9468e9191780cff1beb50e583b0a5717d9721a4cb0fb6cc' 
  AND token = 'IwQsHApd9ZeUKPneA4gNxIFIBbF8ZzWaTlD2ZKdBAvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}