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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ca9d6ff240944b910f22ecb66d204733f2b95df37987c13c33ec99ed877e74b' 
  AND token = 'u23Ri6MFlhfFdstkAs8pQUwV12FnMP8dM7jR+6i4IEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}