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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b916d9858f0b5f2f52c354623e3cb3f0adff899067efe7ebefbe47a28e24ca8' 
  AND token = 'B9TA8rvD7QwOmUotqHNFdtq0pSbkqrcWLsxhLNOeq9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}