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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cda18afb769fd51493e5b93d7b76e6dc2a17b99a1e41bcbefb164939a7d3d80' 
  AND token = 'qenUkqcDT21xoSlBnb7CfYted2TnPI47wj2Zj8dORwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}