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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48bb9543e0ecb5f231756564a9e5336568656a7b893fb7dd07c002a853efae49' 
  AND token = 'cmqb+93SDNkQqkdQSAQwOrmq83W5StjZO6QelyH2EsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}