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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6645a31c5cef566bbb26fbacf21dae32398432be91e9528971675ec32c8f0bf5' 
  AND token = 'hD3xDgIPZQ/9gxhrE8beOU5exjwRjmyuUMQ37JGRuDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}