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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06bf52a4d359ef4c7c7d9eca5045d0b7dbfaee665e9e008ed8ebc7621fa9ab65' 
  AND token = 'DRd3V3TN7PbzDBUVpwGV2Fy3l8ncWVW3auyR+VMZnrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}