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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aff100d0de86716c13be02c038d327377d1e80be9a13e12dd4fffecbc7a3b117' 
  AND token = 'v94TxW+31+f0PF2C2nj6UeskdfXGNNWWQMcPjPUn6WM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}