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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c9851781e743c1056bb3065704b7794caf1ee4530c5f97c5d0a4b80241f6ff6' 
  AND token = 'i2Wf9rNQQ820C5rvda/5Hi1jx+1WnB9+Mm/EcdyaRWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}