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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f858662a96a7883fef71964d36a099b7d1edb19b03e5ba0ab160221fa3007886' 
  AND token = 'qJ9+yfRAAkhmpCobzrrQU62EFhBwzs6oJEGiEn+k0pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}