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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4655127287c2e71cbb53d695c2720c8b60f7155b468c1d22bbe1e488cdc9e4ed' 
  AND token = 'wXSrZEAct5sZ2tVI4cNiR+fsLu9IzPZTrXtkVL4cuzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}