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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b391636b9fbe17b6827923f6efc983f9f9753866446eedd3941a1b7e6fff4690' 
  AND token = 'HTu8WOmQq6z3czEuIxLGLsEtq1r9HJjrGdFTi2GuoYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}