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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcc03163077409ede2058a9e6bcfc8c224c762db6c6ea82b329720e7572b0b95' 
  AND token = 'Ezj7aDV/NPkY6N8yJLVY04v6xCB4/WXOdHAgAfKJ0d8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}