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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '532ec596d0a491820ad409c5fbabd6070de4911b9e1b01e7ef675bf309e04df9' 
  AND token = 'EzwhcEb6+rJzlpFNFO5BqTqDRmvjXfXpr2ozf5jBkac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}