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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd67a31e23b6df4adefb0df54b7be1b85f6115770aa197d7e348806edabf01e5e' 
  AND token = 'rMO8VLvF8On/r535K4Jo64Ixddjn9ajxSdTI2jqb3Oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}