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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4f552f65ce3eec26f87bee4de3eb3be0f6ab3cb237481431b38e05631f3d7a3' 
  AND token = 'W8lEZj3qhT1UL2gsopyAixPK+w1LB6Ae52BKQdgHXqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}