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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48d38a961427c7f7dd7a3da9d7f7205ebb6e90d3e904013d4278c4ee3c9ea9f3' 
  AND token = 'DME5+4ucOcDHEZ6IwcX2vOYTfiL75nB5Mcflnufoyvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}