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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37817cab428d75a52ab1b3f4065bcd6a761c1acdd8a1adae7e3be258c1fea8cd' 
  AND token = 'AjsPUFrasDaxRbJaqClsAR8gFCCQiumDcj57Ac+TT4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}