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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d9adea919b28be31351cd2900f12345057629189c78bba0b30b38ce9d3bd509' 
  AND token = 'HRSU5cOresOOsV+zPCDO1FgNWb71GkCp96SAWq+CgpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}