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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '712fef34db9370a375a6535c79055e2f85dc84815087defdbc82608c5dfa7086' 
  AND token = 'prZX8UAL0T/u/2N80CZ9WYWoZiCGY3RH9oCJMCeg+2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}