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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd360153c056153409ccc2568bcc0a4f1e7425779fc05ae3f1dc9bc1832deee31' 
  AND token = 'Dh6FBfu1K1nHzz5qb+KL6ZbZx7ivfLyYiP3S2x5GMco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}