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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e81a2886340b408cf811f5dc2e5ddb6ddd283792cb76b6c2c51cdbfb30d1f06a' 
  AND token = 'OWDoeBCjUKcW287QutjgUlflm6Z8jENS9+5wSedD58E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}