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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5343e613cff44340da563592bf99a9b41ec4f55f0fab13b3c94b0f61fad64e64' 
  AND token = 'IZpZ1BYlCjyXuynAZU36rjo5nhXfJOaLmJ5dq4+V4j0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}