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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5edf0288afa1b605d0e9b9a1518bcdf8cff3cc86edbb1cc93d69159f1743644' 
  AND token = 'I55jRP3mvMGC92Vt7/kz9uc07hWLyQo9GRK+EO14gV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}