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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b89d2adfa66a0239e54c636a13c8a6e7f2deeb9bbcd885d07108df80b98c2f' 
  AND token = '12aTSmmY7jj3E6glZ+Wa1HWNNLqy5aFmsvu3E3wrZxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}