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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed63b30f734d7b218b6c4f504fe311a2fe51bcae46934b75aec2019bd11d51ce' 
  AND token = '9sSIyGMzGRCZmwBCc+UfXYZdRLKp9EI9lDTZzSVwuTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}