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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5de7ae51b5c291330beb75f4caa2b72a25ca90e670246e4047a7555051e79ef7' 
  AND token = '0IrSEZuOKRbD9MsPnP9l5J0SeCM6t6Kjf6H5gwVNSr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}