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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c105766b00c24dd390310d456b8a01fe2a342c5025a602f989bd510b7c9c2e07' 
  AND token = 'Q+WC8kDV6MC6AqH3r0RCo1lSrE/l5zZPxsTmpU3I7Pw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}