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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1050f7d5f89d183c19189e077bab7ee01c1603f4853653e6e46c05901eda82fc' 
  AND token = 'LQSTaa4AxsS1WkgOo/4Q2IqLdtz+S+mAtuqBW93RWxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}