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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14261f34f3a13bfa2f830b4b4d6c41afb1b5657d88359b61c0691c16b0dd84f0' 
  AND token = 'q12b0Hh3nDJyarVg3EfLNg48tyFDRw1EoAVDsyNV4uY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}