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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3885f8b579411b66abb4cf9b1b8eaef5c1ae8edb3dea4a0cf4018f5c5c0ea607' 
  AND token = 'E1nTuKwbs9t/kdDBHsT+7cnGhXan4/YNSu+nqXJZSfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}