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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aaa6d47264d959c6d17e990f722f124e8d4f95b6be96193d39d978a2a0ba00d' 
  AND token = '81etk82Ekq/L5Ss/0zOhMrxvwpfMu4JDagPFniax9So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}