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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd531bf902d8967b66c66fcb861e7f01d3fb32a0f90fea1f0dee80c0014f8e775' 
  AND token = 'u3cWrMe7+0WMkht+dWg1W2tUlF/Auq64BNKn75ctkOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}