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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e593541b663edc883d19e45a5ebc585af94b3c25b503facbb6237aba1358070e' 
  AND token = 'EWIH3WPIdqWHS4UjXmgnO51h+lTVyLf/CI2CAJAW+OY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}