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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37720fe5872f937813d2ed09bcf9084d521438cbe21553c801c0c9f015df1199' 
  AND token = 'u1KU0u27yMimsBLAXCNGpL/UG7Yz7CJuD5oBbWXMLDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}