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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70ff8c75e130b26c796b07d4a9b7699b21d2c79068d69b938261f3702e74c215' 
  AND token = '3rfjE5bXCXO/OxgPIs8ct9dmlrPJcnuIhW/vDMcyWEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}