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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59cb59edd6dfd49b9c79a38fcc82041075b51c38d78306ea35cbf0cfcc7819e1' 
  AND token = 'UU8j9NH0O217gneR4UQsjGIF25tMH/5wrDxSOirbF+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}