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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a7475ca3b7337654b0da74d3abed6cc9e2ecde949d0c476d07e9ccc1d3a9501' 
  AND token = 'RdPjn2JZdb9dqSn7gF3z6lxk74XpTNcpTrY6YbMbOh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}