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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd170b9b39b416a3c76339eb8cfc84d15fa21cf81ca160a702adc47719a926ec4' 
  AND token = 'jfImsNE7TZ2s7634VblVzHWg/8Ff7Mdh1Lx51r1DNdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}