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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '795e6a39f0630723c5b25316ca412b25d35d353ad200d21f3804224bee702217' 
  AND token = 'uQtGM1vdXfOBWR2Y2eAEtKXGaHXpZG/gO7vwnnhWpmk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}