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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '918b1d04f6a6c4266daa1e3c69c065e0b06757dc777fa02b72e9b47aef2b6ce1' 
  AND token = '/cyOTmjTAUWbcQGhlIyTEy8HjwW0nN7zGG6kh1sliRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}