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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c3ef455a3ce6e552052e5973b88f2730de31aa9b6de4d4b13daf6bc3fab3f9f' 
  AND token = 'E9DvvzkUacMSMTS62F3HSFHvczue0TMW6wLcvKah/fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}