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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77a8d094eb7d17efca55a8f08d7a372fba713846eee47e1b00a8ed9215e19e51' 
  AND token = 'Jytd9xy3FMYbZqdI3Yx+jC88gsg5gC4ItebieXsRSmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}