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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '865a409551c9876e3af7b3b59be986e97aea9b3987c841706e01361b9e92a3b7' 
  AND token = 'FXahL7LI6jK9ZZ4sr6CNk+QDnVDL/kqK+RD/535QUQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}