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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ecd0338e06621465586d567775a70122a05add9fbb8bc6623cf3730747c64524' 
  AND token = '1colQuAT5RaZ4D3Iy22aQ7BCsFMhrmMQ7lyRd8ovpgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}